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The Influence of cis-Regulatory Elements on DNA Methylation Fidelity
It is now established that, as compared to normal cells, the cancer cell genome has an overall inverse distribution of DNA methylation (“methylome”), i.e., predominant hypomethylation and localized hypermethylation, within “CpG islands” (CGIs). Moreover, although cancer cells have reduced methylatio...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295790/ https://ncbi.nlm.nih.gov/pubmed/22412954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032928 |
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