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Mutation of gene-proximal regulatory elements disrupts human ɛ-, γ-, and β-globin expression in yeast artificial chromosome transgenic mice

Previous studies have defined transcriptional control elements, in addition to the promoters, that both lie near individual human β-globin locus genes and have been implicated in their differential stage-specific regulation during development (i.e., are believed to directly participate in hemoglobin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Qinghui, Bungert, Jörg, Engel, James Douglas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC19271/
https://ncbi.nlm.nih.gov/pubmed/8990180
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