Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling

Natural mitochondrial DNA (mtDNA) mutations enable the inference of clonal relationships among cells. mtDNA can be profiled along with measures of cell state, but has not yet been combined with the massively parallel approaches needed to tackle the complexity of human tissue. Here, we introduce a hi...

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Bibliografiset tiedot
Julkaisussa:Nat Biotechnol
Päätekijät: Lareau, Caleb A., Ludwig, Leif S., Muus, Christoph, Gohil, Satyen H., Zhao, Tongtong, Chiang, Zachary, Pelka, Karin, Verboon, Jeffrey M., Luo, Wendy, Christian, Elena, Rosebrock, Daniel, Getz, Gad, Boland, Genevieve M., Chen, Fei, Buenrostro, Jason D., Hacohen, Nir, Wu, Catherine J., Aryee, Martin J., Regev, Aviv, Sankaran, Vijay G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878580/
https://ncbi.nlm.nih.gov/pubmed/32788668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0645-6
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