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Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking
Our ability to track cellular dynamics in humans over time in vivo has been limited. Here, we demonstrate how somatic mutations in mitochondrial DNA (mtDNA) can be used to longitudinally track the dynamic output of hematopoietic stem and progenitor cells in humans. Over the course of 3 years of bloo...
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| Vydáno v: | Blood Adv |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6929387/ https://ncbi.nlm.nih.gov/pubmed/31841597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001196 |
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