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Hematopoiesis is not clonal in healthy elderly women
Clonality assays, based on X-chromosome inactivation, discriminate active from inactive alleles. Skewing of X-chromosome allelic usage, based on preferential methylation of one of the HUMARA alleles, was reported as evidence of clonal hematopoiesis in approximately 30% of elderly women. Using a quan...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2569172/ https://ncbi.nlm.nih.gov/pubmed/18641369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-143925 |
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