JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells

Lifelong multilineage hematopoiesis critically depends on rare hematopoietic stem cells (HSCs) that reside in the hypoxic bone marrow microenvironment. Although the role of the canonical oxygen sensor hypoxia-inducible factor prolyl hydroxylase has been investigated extensively in hematopoiesis, the...

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Udgivet i:Blood Adv
Main Authors: Lawson, Hannah, Sepulveda, Catarina, van de Lagemaat, Louie N., Durko, Jozef, Barile, Melania, Tavosanis, Andrea, Georges, Elise, Shmakova, Alena, Timms, Penny, Carter, Roderick N., Allen, Lewis, Campos, Joana, Vukovic, Milica, Guitart, Amelie V., Giles, Peter, O’Shea, Marie, Vernimmen, Douglas, Morton, Nicholas M., Rodrigues, Neil P., Göttgens, Berthold, Schofield, Christopher J., Lengeling, Andreas, O’Carroll, Dónal, Kranc, Kamil R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2021
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876897/
https://ncbi.nlm.nih.gov/pubmed/33560400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002702
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