A time and single-cell resolved model of murine bone marrow hematopoiesis

The paradigmatic hematopoietic tree model is increasingly recognized to be limited as it is based on heterogeneous populations and largely inferred from non-homeostatic cell fate assays. Here, we combine persistent labeling with time-series single-cell RNA-Seq to build a real-time, quantitative mode...

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Publicat a:Cell Stem Cell
Autors principals: Kucinski, Iwo, Campos, Joana, Barile, Melania, Severi, Francesco, Bohin, Natacha, Moreira, Pedro N, Allen, Lewis, Lawson, Hannah, Haltalli, Myriam L R, Kinston, Sarah J, O’Carroll, Dónal, Kranc, Kamil R, Göttgens, Berthold
Format: Artigo
Idioma:Inglês
Publicat: 2024
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615671/
https://ncbi.nlm.nih.gov/pubmed/38183977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2023.12.001
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