A time and single-cell resolved model of murine bone marrow hematopoiesis

The paradigmatic hematopoietic tree model is increasingly recognized to be limited as it is based on heterogeneous populations and largely inferred from non-homeostatic cell fate assays. Here, we combine persistent labeling with time-series single-cell RNA-Seq to build a real-time, quantitative mode...

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Veröffentlicht in:Cell Stem Cell
Hauptverfasser: Kucinski, Iwo, Campos, Joana, Barile, Melania, Severi, Francesco, Bohin, Natacha, Moreira, Pedro N, Allen, Lewis, Lawson, Hannah, Haltalli, Myriam L R, Kinston, Sarah J, O’Carroll, Dónal, Kranc, Kamil R, Göttgens, Berthold
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2024
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615671/
https://ncbi.nlm.nih.gov/pubmed/38183977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2023.12.001
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