NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells

Spermatogonial stem cells (SSCs) sustain spermatogenesis and fertility throughout adult male life. The conserved RNA-binding protein NANOS2 is essential for the maintenance of SSCs, but its targets and mechanisms of function are not fully understood. Here, we generated a fully functional epitope-tag...

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Pubblicato in:iScience
Autori principali: Codino, Azzurra, Turowski, Tomasz, van de Lagemaat, Louie N., Ivanova, Ivayla, Tavosanis, Andrea, Much, Christian, Auchynnikava, Tania, Vasiliauskaitė, Lina, Morgan, Marcos, Rappsilber, Juri, Allshire, Robin C., Kranc, Kamil R., Tollervey, David, O'Carroll, Dónal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8271163/
https://ncbi.nlm.nih.gov/pubmed/34278268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102762
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