A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

Several developmental stages of spermatogenesis are transcriptionally quiescent which presents major challenges associated with the regulation of gene expression. Here we identify that the zygotene to pachytene transition is not only associated with the resumption of transcription but also a wave of...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Morgan, Marcos, Kabayama, Yuka, Much, Christian, Ivanova, Ivayla, Di Giacomo, Monica, Auchynnikava, Tatsiana, Monahan, Jack Michael, Vitsios, Dimitrios Michael, Vasiliauskaitė, Lina, Comazzetto, Stefano, Rappsilber, Juri, Allshire, Robin Campbell, Porse, Bo Torben, Enright, Anton James, O’Carroll, Dónal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420129/
https://ncbi.nlm.nih.gov/pubmed/30617251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0128-1
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