A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

Several developmental stages of spermatogenesis are transcriptionally quiescent which presents major challenges associated with the regulation of gene expression. Here we identify that the zygotene to pachytene transition is not only associated with the resumption of transcription but also a wave of...

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Publicat a:Cell Res
Autors principals: Morgan, Marcos, Kabayama, Yuka, Much, Christian, Ivanova, Ivayla, Di Giacomo, Monica, Auchynnikava, Tatsiana, Monahan, Jack Michael, Vitsios, Dimitrios Michael, Vasiliauskaitė, Lina, Comazzetto, Stefano, Rappsilber, Juri, Allshire, Robin Campbell, Porse, Bo Torben, Enright, Anton James, O’Carroll, Dónal
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420129/
https://ncbi.nlm.nih.gov/pubmed/30617251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0128-1
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