mRNA 3′ uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome

A fundamental principle in biology is that the program for early development is established during oogenesis in the form of the maternal transcriptome1,2. How the maternal transcriptome acquires the appropriate content and dosage of transcripts is not fully understood. Here we show that TUT4/7-media...

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Publicado no:Nature
Main Authors: Morgan, Marcos, Much, Christian, DiGiacomo, Monica, Azzi, Chiara, Ivanova, Ivayla, Vitsios, Dimitrios M., Pistolic, Jelena, Collier, Paul, Moreira, Pedro, Benes, Vladimir, Enright, Anton J., O’Carroll, Dónal
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768236/
https://ncbi.nlm.nih.gov/pubmed/28792939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23318
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