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mRNA 3′ uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome

A fundamental principle in biology is that the program for early development is established during oogenesis in the form of the maternal transcriptome1,2. How the maternal transcriptome acquires the appropriate content and dosage of transcripts is not fully understood. Here we show that TUT4/7-media...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nature
Päätekijät: Morgan, Marcos, Much, Christian, DiGiacomo, Monica, Azzi, Chiara, Ivanova, Ivayla, Vitsios, Dimitrios M., Pistolic, Jelena, Collier, Paul, Moreira, Pedro, Benes, Vladimir, Enright, Anton J., O’Carroll, Dónal
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768236/
https://ncbi.nlm.nih.gov/pubmed/28792939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23318
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