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Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein

Dicer is a large multi-domain protein responsible for the ultimate step of microRNA and short-interfering RNA biogenesis. In human and mouse cell lines, Dicer has been shown to be important in the nuclear clearance of dsRNA as well as the establishment of chromatin modifications. Here we set out to...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Much, Christian, Auchynnikava, Tania, Pavlinic, Dinko, Buness, Andreas, Rappsilber, Juri, Benes, Vladimir, Allshire, Robin, O’Carroll, Dónal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890738/
https://ncbi.nlm.nih.gov/pubmed/27254021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006095
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