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Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein

Dicer is a large multi-domain protein responsible for the ultimate step of microRNA and short-interfering RNA biogenesis. In human and mouse cell lines, Dicer has been shown to be important in the nuclear clearance of dsRNA as well as the establishment of chromatin modifications. Here we set out to...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Much, Christian, Auchynnikava, Tania, Pavlinic, Dinko, Buness, Andreas, Rappsilber, Juri, Benes, Vladimir, Allshire, Robin, O’Carroll, Dónal
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890738/
https://ncbi.nlm.nih.gov/pubmed/27254021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006095
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