Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein

Dicer is a large multi-domain protein responsible for the ultimate step of microRNA and short-interfering RNA biogenesis. In human and mouse cell lines, Dicer has been shown to be important in the nuclear clearance of dsRNA as well as the establishment of chromatin modifications. Here we set out to...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Much, Christian, Auchynnikava, Tania, Pavlinic, Dinko, Buness, Andreas, Rappsilber, Juri, Benes, Vladimir, Allshire, Robin, O’Carroll, Dónal
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890738/
https://ncbi.nlm.nih.gov/pubmed/27254021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006095
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