TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing

The PIWI protein MIWI2 and its associated PIWI-interacting RNAs (piRNAs) instruct DNA methylation of young active transposable elements (TEs) in the male germline. piRNAs are proposed to recruit MIWI2 to the transcriptionally active TE loci by base pairing to nascent transcripts, however the downstr...

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Publicado no:Nat Commun
Main Authors: Schöpp, Theresa, Zoch, Ansgar, Berrens, Rebecca V., Auchynnikava, Tania, Kabayama, Yuka, Vasiliauskaitė, Lina, Rappsilber, Juri, Allshire, Robin C., O’Carroll, Dónal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385494/
https://ncbi.nlm.nih.gov/pubmed/32719317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17372-5
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