JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells

Lifelong multilineage hematopoiesis critically depends on rare hematopoietic stem cells (HSCs) that reside in the hypoxic bone marrow microenvironment. Although the role of the canonical oxygen sensor hypoxia-inducible factor prolyl hydroxylase has been investigated extensively in hematopoiesis, the...

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Bibliografske podrobnosti
izdano v:Blood Adv
Main Authors: Lawson, Hannah, Sepulveda, Catarina, van de Lagemaat, Louie N., Durko, Jozef, Barile, Melania, Tavosanis, Andrea, Georges, Elise, Shmakova, Alena, Timms, Penny, Carter, Roderick N., Allen, Lewis, Campos, Joana, Vukovic, Milica, Guitart, Amelie V., Giles, Peter, O’Shea, Marie, Vernimmen, Douglas, Morton, Nicholas M., Rodrigues, Neil P., Göttgens, Berthold, Schofield, Christopher J., Lengeling, Andreas, O’Carroll, Dónal, Kranc, Kamil R.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2021
Teme:
Hematopoiesis and Stem Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876897/
https://ncbi.nlm.nih.gov/pubmed/33560400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002702
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