The role of glycosylation in the N-terminus of the hemagglutinin of a unique H4N2 with a natural polybasic cleavage site in virus fitness in vitro and in vivo

To date, only low pathogenic (LP) H5 and H7 avian influenza viruses (AIV) have been observed to naturally shift to a highly pathogenic (HP) phenotype after mutation of the monobasic hemagglutinin (HA) cleavage site (HACS) to polybasic motifs. The LPAIV monobasic HACS is activated by tissue-restricte...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Gischke, Marcel, Bagato, Ola, Breithaupt, Angele, Scheibner, David, Blaurock, Claudia, Vallbracht, Melina, Karger, Axel, Crossley, Beate, Veits, Jutta, Böttcher-Friebertshäuser, Eva, Mettenleiter, Thomas C., Abdelwhab, Elsayed M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872060/
https://ncbi.nlm.nih.gov/pubmed/33538209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2021.1881344
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados