Highly Pathogenic H5N1 Influenza Viruses Carry Virulence Determinants beyond the Polybasic Hemagglutinin Cleavage Site

Highly pathogenic avian influenza viruses (HPAIV) originate from avirulent precursors but differ from all other influenza viruses by the presence of a polybasic cleavage site in their hemagglutinins (HA) of subtype H5 or H7. In this study, we investigated the ability of a low-pathogenic avian H5N1 s...

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Main Authors: Bogs, Jessica, Veits, Jutta, Gohrbandt, Sandra, Hundt, Jana, Stech, Olga, Breithaupt, Angele, Teifke, Jens P., Mettenleiter, Thomas C., Stech, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910732/
https://ncbi.nlm.nih.gov/pubmed/20676399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011826
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