Acquisition of a Polybasic Hemagglutinin Cleavage Site by a Low-Pathogenic Avian Influenza Virus Is Not Sufficient for Immediate Transformation into a Highly Pathogenic Strain

Highly pathogenic avian influenza viruses (HPAIV) differ from all other strains by a polybasic cleavage site in their hemagglutinin. All these HPAIV share the H5 or H7 subtype. In order to investigate whether the acquisition of a polybasic cleavage site by an avirulent avian influenza virus strain w...

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Detalhes bibliográficos
Main Authors: Stech, Olga, Veits, Jutta, Weber, Siegfried, Deckers, Daniela, Schröer, Diana, Vahlenkamp, Thomas W., Breithaupt, Angele, Teifke, Jens, Mettenleiter, Thomas C., Stech, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681970/
https://ncbi.nlm.nih.gov/pubmed/19297482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02649-08
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