Avian influenza virus hemagglutinins H2, H4, H8, and H14 support a highly pathogenic phenotype

High-pathogenic avian influenza viruses (HPAIVs) evolve from low-pathogenic precursors specifying the HA serotypes H5 or H7 by acquisition of a polybasic HA cleavage site. As the reason for this serotype restriction has remained unclear, we aimed to distinguish between compatibility of a polybasic c...

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Detalhes bibliográficos
Main Authors: Veits, Jutta, Weber, Siegfried, Stech, Olga, Breithaupt, Angele, Gräber, Marcus, Gohrbandt, Sandra, Bogs, Jessica, Hundt, Jana, Teifke, Jens P., Mettenleiter, Thomas C., Stech, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289369/
https://ncbi.nlm.nih.gov/pubmed/22308331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109397109
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