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Optimal two-stage design of single arm Phase II clinical trials based on median event time test
The Phase II clinical trials aim to assess the therapeutic efficacy of a new drug. The therapeutic efficacy has been often quantified by response rate such as overall response rate or survival probability in the Phase II setting. However, there is a strong desire to use survival time, which is the g...
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| Publicat a: | PLoS One |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7870013/ https://ncbi.nlm.nih.gov/pubmed/33556130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246448 |
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