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Optimal two-stage design of single arm Phase II clinical trials based on median event time test

The Phase II clinical trials aim to assess the therapeutic efficacy of a new drug. The therapeutic efficacy has been often quantified by response rate such as overall response rate or survival probability in the Phase II setting. However, there is a strong desire to use survival time, which is the g...

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書目詳細資料
發表在:PLoS One
主要作者: Park, Yeonhee
格式: Artigo
語言:Inglês
出版: Public Library of Science 2021
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870013/
https://ncbi.nlm.nih.gov/pubmed/33556130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246448
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