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Phase II clinical trials with time-to-event endpoints: Optimal two-stage designs with one-sample log-rank test
Phase II clinical trials are often conducted to determine whether a new treatment is sufficiently promising to warrant a major controlled clinical evaluation against a standard therapy. We consider single-arm phase II clinical trials with right censored survival time responses where the ordinary one...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4013236/ https://ncbi.nlm.nih.gov/pubmed/24338995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6073 |
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