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Phase II Trials for Heterogeneous Patient Populations with a Time-to-Event Endpoint
In this paper, we consider a single-arm phase II trial with a time-to-event end-point. We assume that the study population has multiple subpopulations with different prognosis, but the study treatment is expected to be similarly efficacious across the subpopulations. We review a stratified one-sampl...
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| Publicat a: | Med Res Arch |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5749428/ https://ncbi.nlm.nih.gov/pubmed/29302620 |
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