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Phase II Trials for Heterogeneous Patient Populations with a Time-to-Event Endpoint

In this paper, we consider a single-arm phase II trial with a time-to-event end-point. We assume that the study population has multiple subpopulations with different prognosis, but the study treatment is expected to be similarly efficacious across the subpopulations. We review a stratified one-sampl...

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Vydáno v:Med Res Arch
Hlavní autor: Jung, Sin-Ho
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749428/
https://ncbi.nlm.nih.gov/pubmed/29302620
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