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Phase II Cancer Clinical Trials with Heterogeneous Patient Populations

The patient population for a phase II trial often consists of multiple subgroups in terms of risk level. In this case, a popular design approach is to specify the response rate and the prevalence of each subgroup, to calculate the response rate of the whole population by the weighted average of the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Jung, Sin-Ho, Chang, Myron N., Kang, Sun J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324125/
https://ncbi.nlm.nih.gov/pubmed/22251176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2010.536873
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