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Improved Two-Stage Tests for Stratified Phase II Cancer Clinical Trials

In a single-arm, two-stage, phase II cancer clinical trial for efficacy screening of cytotoxic agents, a common primary endpoint is a binary (yes/no) patient response to treatment. Usually, fixed decision boundaries are used in binomial tests to determine whether the study treatment is promising eno...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Chang, Myron N., Shuster, Jonathan J., Hou, Wei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972010/
https://ncbi.nlm.nih.gov/pubmed/22422466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5314
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