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Improved Two-Stage Tests for Stratified Phase II Cancer Clinical Trials
In a single-arm, two-stage, phase II cancer clinical trial for efficacy screening of cytotoxic agents, a common primary endpoint is a binary (yes/no) patient response to treatment. Usually, fixed decision boundaries are used in binomial tests to determine whether the study treatment is promising eno...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972010/ https://ncbi.nlm.nih.gov/pubmed/22422466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5314 |
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