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What inference for two-stage phase II trials?
BACKGROUND: Simon’s two-stage designs are widely used for cancer phase II trials. These methods rely on statistical testing and thus allow controlling the type I and II error rates, while accounting for the interim analysis. Estimation after such trials is however not straightforward, and several di...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445829/ https://ncbi.nlm.nih.gov/pubmed/22867439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-12-117 |
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