Llwytho...
Phase II Two-Stage Single-Arm Clinical Trials for Testing Toxicity Levels
Simon’s two-stage designs are frequently used in phase II single-arm trials for efficacy studies. In safety studies, a main concern is that there may be too many patients who experience an adverse event. We show that Simon’s two-stage designs for efficacy studies can be similarly used to design a tw...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Commun Stat Appl Methods |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6522135/ https://ncbi.nlm.nih.gov/pubmed/31106162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29220/CSAM.2019.26.2.163 |
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