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Design of phase II non-inferiority trials
With the development of inexpensive treatment regimens and less invasive surgical procedures, we are confronted with non-inferiority study objectives. A non-inferiority phase III trial requires a roughly four times larger sample size than that of a similar standard superiority trial. Because of the...
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| 發表在: | Contemp Clin Trials Commun |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546322/ https://ncbi.nlm.nih.gov/pubmed/28798964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2017.04.008 |
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