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Mixed response and time-to-event endpoints for multistage single-arm phase II design
BACKGROUND: The objective of phase II cancer clinical trials is to determine if a treatment has sufficient activity to warrant further study. The efficiency of a conventional phase II trial design has been the object of considerable debate, particularly when the study regimen is characteristically c...
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| 出版年: | Trials |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460691/ https://ncbi.nlm.nih.gov/pubmed/26037094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-015-0743-9 |
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