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Mixed response and time-to-event endpoints for multistage single-arm phase II design

BACKGROUND: The objective of phase II cancer clinical trials is to determine if a treatment has sufficient activity to warrant further study. The efficiency of a conventional phase II trial design has been the object of considerable debate, particularly when the study regimen is characteristically c...

詳細記述

保存先:
書誌詳細
出版年:Trials
主要な著者: Lai, Xin, Zee, Benny Chung-Ying
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460691/
https://ncbi.nlm.nih.gov/pubmed/26037094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-015-0743-9
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