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Single-Arm Phase II Group Sequential Trial Design with Survival Endpoint at a Fixed Time Point

In this paper, three non-parametric test statistics are proposed to design single-arm phase II group sequential trials for monitoring survival probability. The small-sample properties of these test statistics are studied through simulations. Sample size formulas are derived for the fixed sample test...

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Detalhes bibliográficos
Publicado no:Stat Biopharm Res
Main Authors: Wu, Jianrong, Xiong, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589207/
https://ncbi.nlm.nih.gov/pubmed/28890756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2014.923325
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