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Group Sequential Survival Trial Design and Monitoring Using the Log-Rank Test

For randomized group sequential survival trial designs with unbalanced treatment allocation, the widely used Schoenfeld formula is inaccurate, and the commonly used information time as the ratio of number of events at interim look to the number of events at the end of trial can be biased. In this pa...

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Detalhes bibliográficos
Publicado no:Stat Biopharm Res
Main Authors: Wu, Jianrong, Xiong, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619877/
https://ncbi.nlm.nih.gov/pubmed/28966722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2016.1189355
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