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Group Sequential Survival Trial Design and Monitoring Using the Log-Rank Test

For randomized group sequential survival trial designs with unbalanced treatment allocation, the widely used Schoenfeld formula is inaccurate, and the commonly used information time as the ratio of number of events at interim look to the number of events at the end of trial can be biased. In this pa...

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Библиографические подробности
Опубликовано в: :Stat Biopharm Res
Главные авторы: Wu, Jianrong, Xiong, Xiaoping
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619877/
https://ncbi.nlm.nih.gov/pubmed/28966722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2016.1189355
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