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Single-Arm Phase II Survival Trial Design Under the Proportional Hazards Model
For designing single-arm phase II trials with time-to-event endpoints, a sample size formula is derived for the modified one-sample log-rank test under the proportional hazards model. The derived formula enables new methods for designing trials that allow a flexible choice of the underlying survival...
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| Izdano u: | Stat Biopharm Res |
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| Glavni autor: | |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5619878/ https://ncbi.nlm.nih.gov/pubmed/28966721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2016.1174147 |
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