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Optimal two-stage designs based on restricted mean survival time for a single-arm study
Restricted mean survival time is an alternative measure of treatment effect to hazard ratio in clinical trials with time-to-event outcome. The current methods have been focused on one-stage designs. In this article, we propose optimal two-stage designs for a single-arm study with the smallest expect...
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| Publicado no: | Contemp Clin Trials Commun |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7856426/ https://ncbi.nlm.nih.gov/pubmed/33553801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2021.100732 |
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