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Optimal two-stage designs based on restricted mean survival time for a single-arm study

Restricted mean survival time is an alternative measure of treatment effect to hazard ratio in clinical trials with time-to-event outcome. The current methods have been focused on one-stage designs. In this article, we propose optimal two-stage designs for a single-arm study with the smallest expect...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Contemp Clin Trials Commun
मुख्य लेखक: Shan, Guogen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856426/
https://ncbi.nlm.nih.gov/pubmed/33553801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2021.100732
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