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Replication-independent instability of Friedreich’s ataxia GAA repeats during chronological aging
Nearly 50 hereditary diseases result from the inheritance of abnormally long repetitive DNA microsatellites. While it was originally believed that the size of inherited repeats is the key factor in disease development, it has become clear that somatic instability of these repeats throughout an indiv...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7865128/ https://ncbi.nlm.nih.gov/pubmed/33495349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013080118 |
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