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Effects of Friedreich's ataxia GAA repeats on DNA replication in mammalian cells

Friedreich's ataxia (FRDA) is a common hereditary degenerative neuro-muscular disorder caused by expansions of the (GAA)n repeat in the first intron of the frataxin gene. The expanded repeats from parents frequently undergo further significant length changes as they are passed on to progeny. Ex...

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Detalhes bibliográficos
Main Authors: Chandok, Gurangad S., Patel, Mayank P., Mirkin, Sergei M., Krasilnikova, Maria M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351192/
https://ncbi.nlm.nih.gov/pubmed/22262734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks021
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