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Replication Stalling at Friedreich's Ataxia (GAA)(n) Repeats In Vivo

Friedreich's ataxia (GAA)(n) repeats of various lengths were cloned into a Saccharymyces cerevisiae plasmid, and their effects on DNA replication were analyzed using two-dimensional electrophoresis of replication intermediates. We found that premutation- and disease-size repeats stalled the rep...

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Detalhes bibliográficos
Main Authors: Krasilnikova, Maria M., Mirkin, Sergei M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC355872/
https://ncbi.nlm.nih.gov/pubmed/14993268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2286-2295.2004
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