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Heat Shrinking DNA Nanoparticles for In Vivo Gene Delivery
The particle size of a PEG-peptide DNA nanoparticle is key determinant of its biodistribution following i.v. dosing. To successfully cross the fenestrated endothelial cells of the liver, DNA nanoparticles should be less than 100 nm in diameter. In addition, DNA nanoparticles must be sufficiently cha...
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| Pubblicato in: | Gene Ther |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7863632/ https://ncbi.nlm.nih.gov/pubmed/31900424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-019-0117-0 |
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