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PEG-Peptide Inhibition of Scavenger Receptor Uptake of Nanoparticles by the Liver

PEGylated polylysine peptides represent a new class of scavenger receptor inhibitors that may find utility at inhibiting DNA nanoparticle uptake by Kupffer cells in the liver. PEG-peptides inhibit scavenger receptors in the liver by a novel mechanism involving in situ formation of albumin nanopartic...

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Publicat a:Mol Pharm
Autors principals: Allen, Rondine J., Mathew, Basil, Rice, Kevin G.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413502/
https://ncbi.nlm.nih.gov/pubmed/30052459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b00355
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