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Nanoparticle Targeting and Cholesterol Flux Through Scavenger Receptor Type B-1 Inhibits Cellular Exosome Uptake

Exosomes are nanoscale vesicles that mediate intercellular communication. Cellular exosome uptake mechanisms are not well defined partly due to the lack of specific inhibitors of this complex cellular process. Exosome uptake depends on cholesterol-rich membrane microdomains called lipid rafts, and c...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Plebanek, Michael P., Mutharasan, R. Kannan, Volpert, Olga, Matov, Alexandre, Gatlin, Jesse C., Thaxton, C. Shad
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625174/
https://ncbi.nlm.nih.gov/pubmed/26511855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15724
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