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Scavenger Receptors Mediate Cellular Uptake of Polyvalent Oligonucleotide-Functionalized Gold Nanoparticles

Mammalian cells have been shown to internalize oligonucleotide-functionalized gold nanoparticles (DNA-Au NPs or siRNA-Au NPs) without the aid of auxiliary transfection agents and use them to initiate an antisense or RNAi response. Previous studies have shown that the dense monolayer of oligonucleoti...

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Autors principals: Patel, Pinal C., Giljohann, David A., Daniel, Weston L., Zheng, Dan, Prigodich, Andrew E., Mirkin, Chad A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241523/
https://ncbi.nlm.nih.gov/pubmed/21070003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc1002423
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