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Heat Shrinking DNA Nanoparticles for In Vivo Gene Delivery

The particle size of a PEG-peptide DNA nanoparticle is key determinant of its biodistribution following i.v. dosing. To successfully cross the fenestrated endothelial cells of the liver, DNA nanoparticles should be less than 100 nm in diameter. In addition, DNA nanoparticles must be sufficiently cha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Gene Ther
Päätekijät: Mathew, Basil, Ramanathan, Raghu, Delvaux, Nathan, Poliskey, Jacob, Rice, Kevin G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863632/
https://ncbi.nlm.nih.gov/pubmed/31900424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-019-0117-0
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