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Heat Shrinking DNA Nanoparticles for In Vivo Gene Delivery
The particle size of a PEG-peptide DNA nanoparticle is key determinant of its biodistribution following i.v. dosing. To successfully cross the fenestrated endothelial cells of the liver, DNA nanoparticles should be less than 100 nm in diameter. In addition, DNA nanoparticles must be sufficiently cha...
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| Publicado no: | Gene Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7863632/ https://ncbi.nlm.nih.gov/pubmed/31900424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-019-0117-0 |
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