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Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size

Covalent fluorescent labels are important tools for monitoring the in vitro and in vivo localization of plasmid DNA nanoparticles, but must meet several criteria including high DNA labeling efficiencies and minimal impact on nanoparticle size. We developed a novel fluorescent labeling strategy utili...

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Detalhes bibliográficos
Publicado no:Anal Biochem
Main Authors: Delvaux, Nathan A., Mathew, Basil, Rice, Kevin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870724/
https://ncbi.nlm.nih.gov/pubmed/32783899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2020.113895
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