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Thrombin-Par1 signaling axis disrupts COP9 signalosome subunit 3-mediated ABCA1 stabilization in inducing foam cell formation and atherogenesis

ATP-binding cassette transporters A1 (ABCA1) and G1 (ABCG1) play a vital role in promoting cholesterol efflux. Although, the dysregulation of these transporters was attributed as one of the mechanisms of atherogenesis, what renders their dysfunction is not well explored. Previously, we have reported...

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Dades bibliogràfiques
Publicat a:Cell Death Differ
Autors principals: Boro, Monoranjan, Govatati, Suresh, Kumar, Raj, Singh, Nikhlesh K., Pichavaram, Prahalathan, Traylor, James G., Orr, A. Wayne, Rao, Gadiparthi N.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862243/
https://ncbi.nlm.nih.gov/pubmed/32968199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00623-9
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