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LIM and cysteine-rich domains 1 is required for thrombin-induced smooth muscle cell proliferation and promotes atherogenesis

Restenosis arises after vascular injury and is characterized by arterial wall thickening and decreased arterial lumen space. Vascular injury induces the production of thrombin, which in addition to its role in blood clotting acts as a mitogenic and chemotactic factor. In exploring the molecular mech...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Janjanam, Jagadeesh, Zhang, Baolin, Mani, Arul M., Singh, Nikhlesh K., Traylor, James G., Orr, A. Wayne, Rao, Gadiparthi N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836108/
https://ncbi.nlm.nih.gov/pubmed/29326163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000866
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