NFATc1-E2F1-LMCD1-mediated IL-33 expression by thrombin is required for injury-induced neointima formation

OBJECTIVE: IL-33 has been shown to play a role in endothelial dysfunction but its role in atherosclerosis is controversial. Therefore, the purpose of this study is to examine its role in vascular wall remodeling following injury. APPROACH AND RESULTS: Thrombin induced IL-33 expression in a time depe...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Govatati, Suresh, Pichavaram, Prahalathan, Janjanam, Jagadeesh, Zhang, Baolin, Singh, Nikhlesh K., Mani, Arul M., Traylor, James G., Orr, A. Wayne, Rao, Gadiparthi N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540998/
https://ncbi.nlm.nih.gov/pubmed/31043075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312729
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