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NFATc1-E2F1-LMCD1-mediated IL-33 expression by thrombin is required for injury-induced neointima formation

OBJECTIVE: IL-33 has been shown to play a role in endothelial dysfunction but its role in atherosclerosis is controversial. Therefore, the purpose of this study is to examine its role in vascular wall remodeling following injury. APPROACH AND RESULTS: Thrombin induced IL-33 expression in a time depe...

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Détails bibliographiques
Publié dans:Arterioscler Thromb Vasc Biol
Auteurs principaux: Govatati, Suresh, Pichavaram, Prahalathan, Janjanam, Jagadeesh, Zhang, Baolin, Singh, Nikhlesh K., Mani, Arul M., Traylor, James G., Orr, A. Wayne, Rao, Gadiparthi N.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540998/
https://ncbi.nlm.nih.gov/pubmed/31043075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312729
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